Brain
Published research on Brain.

A 2025 Nature Aging study found that hippocampal ferritin light chain 1 (FTL1) rose with age in mouse neurons, tracked poorer cognition, and became experimentally reversible in old mice. Thi…
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A Cell Reports study tied C9orf72-related ALS/FTD inflammation to a gut-bacterial product: inflammatory microbial glycogen appeared in 15 of 22 ALS fecal samples, 1 of 1 C9orf72-frontotempor…
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A 2026 automated MRI analysis of 153 adults with first cortical middle cerebral artery stroke found that remote deep gray nuclei changes were already measurable within 21 days, and 2 asymmet…
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A 2026 Australian study involving 2,192 dementia-free adults found that each 10% higher ultra-processed food intake was associated with 0.05-point lower attention and 0.24-point higher modif…
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A 2026 Molecular Psychiatry study found that oral FP802 disrupted the NMDAR/TRPM4 death complex and preserved memory-task performance in 5xFAD Alzheimer’s mice treated for 3 months.1 The fin…
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In APP/PS1 Alzheimer's model mice, deleting PTP1B or treating with the allosteric inhibitor DPM-1003 improved memory behavior, lowered amyloid burden, and pushed microglia toward SYK-driven …
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Cocaine relapse circuitry looks different when alcohol is part of the history. In a rat model, inhibiting prelimbic cortex neurons projecting to the nucleus accumbens core blocked cue-trigge…
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