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MicroRNAs as Blood-Based Biomarkers for Early ADHD Diagnosis in Children

Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset neurodevelopmental disorder characterized by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity. While highly heritable, the heterogeneity of clinical presentation suggests complex interactions between genetic and environmental risk factors. A new study suggests that it may be possible to diagnose ADHD or detect ADHD susceptibility risk in children …

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Solriamfetol for ADHD in Adults: A New Alternative Treatment?

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by problems with inattention, hyperactivity, and impulsivity. While ADHD has historically been considered a disorder of childhood, it is now known that symptoms frequently persist into adulthood. A new pilot study published in the Journal of Clinical Psychiatry provides the first data indicating that a newer …

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How Long Does It Take For Adderall to “Kick In”?

Adderall is a psychostimulant medication [of the phenethylamine classification] comprised of multiple amphetamine isomers: dextroamphetamine (~75%) and levoamphetamine (~25%).  In medical settings, Adderall is frequently prescribed for the management of ADHD (attention-deficit/hyperactivity disorder) and narcolepsy.  Less commonly, Adderall is utilized off-label as an adjunct in the management of refractory neuropsychiatric disorders such as: chronic fatigue …

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Vyvanse Side Effects & Adverse Reactions (List)

Vyvanse (Lisdexamfetamine) is a prodrug comprised of the amino acid L-lysine coupled with dextroamphetamine, hence its chemical name “lis-dexamfetamine.”  As a prodrug, Vyvanse is inactive until ingested and enzymatically metabolized into l-lysine (an amino acid) and dextroamphetamine (a psychostimulant), the latter of which has been deemed effective for the treatment of ADHD and binge eating …

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How Long Does Adderall Stay In Your System?

Adderall is a prescription medication manufactured by Shire Pharmaceuticals containing a mixture of amphetamine salts (75% dextroamphetamine and 25% levoamphetamine).  It was first approved by the FDA in 1996 for the management of ADHD (attention-deficit/hyperactivity disorder) and was later approved for the treatment of narcolepsy.  The medication is manufactured in multiple formats including: an immediate …

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Phentermine For ADHD: An Uninvestigated Treatment

Phentermine is an anorectic medication utilized principally for the short-term treatment of obesity as an adjunct to caloric restriction, dietary modifications, and physical exercise.  It is formally classified as a psychostimulant due to the fact that it increases mental and physical arousal [via sympathomimetic mechanisms].  Specifically, phentermine facilitates central and peripheral catecholamine release (primarily of …

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Adderall Tolerance: Causes & How To Prevent It

Nearly all individuals taking Adderall can attest to the fact that its psychostimulatory effect is most potent after an initial “first-time” dosage.  Thereafter, its efficacy is generally maintained for weeks, or perhaps months after the initial dosage with favorable results.  However, eventually Adderall users may notice that its therapeutic psychostimulation seems to have dwindled and/or …

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