MentalHealthDaily

Psilocybin for Depression: Optimal Dosages for Antidepressant Effects (2023 Review)

Recent research has provided compelling evidence on the therapeutic potential of psilocybin, a naturally occurring psychedelic, in treating depression. A systematic review and dose-response meta-analysis shed light on the optimal dosage of psilocybin for depression, revealing variations in effectiveness based on patient subgroups and associated risks. Highlights: Psilocybin showed significant antidepressant effects, with optimal dosages …

Psychedelics vs. Epilepsy & Seizures: Effective Treatment or Exacerbation? (2023 Review)

by GLOOM

Psychedelic compounds, long associated with the fringes of medicine and spirituality, are now at the forefront of a radical shift in neurology and psychiatry. Decades of clinical trials have begun to unravel the therapeutic potentials of these substances, revealing promising outcomes in the treatment of various psychiatric disorders. However, a notable gap in this burgeoning …

Psilocybin for Major Depression in Adults (2023 Evidence Review)

by GLOOM

The emerging research into psilocybin, a classical psychedelic, reveals its significant potential in treating Major Depressive Disorder (MDD). Historically used in spiritual and shamanic practices, psilocybin’s recent clinical studies have opened new avenues in mental health treatment, challenging traditional antidepressants like SSRIs. Highlights: Psilocybin’s Historical & Clinical Relevance: A natural compound used for millennia, recent …

Psychedelics for Depression: Targeting the 5-HT2A Receptor & Beyond (2023 Study)

by GLOOM

The quest for effective treatments for Major Depressive Disorder (MDD) has taken a revolutionary turn with the exploration of psychedelic compounds. Recent research has evaluated the potential of substances like psilocybin and lisuride, offering new hope for patients unresponsive to traditional antidepressants. Highlights: Traditional Limitations: Standard antidepressants often fail to provide relief for 30% of …

How Long Do “Shrooms” Stay In Your System? (Psilocybin)

by GLOOM

“Shrooms” commonly refers to over 200 species of mushrooms containing the active psychedelic compound known as “psilocybin.” Psilocybin itself is a prodrug, meaning it is inactive until ingested and broken down (metabolized) within the body. Upon metabolism of psilocybin, it is converted to the active metabolite “psilocin” which functions primarily as a 5-HT2A receptor partial …

Using Psilocybin (Magic Mushrooms) To Treat Depression

by GLOOM

Would you have ever thought that the hallucinogenic drug Psilocybin, commonly referred to as “magic mushrooms” could help cure you of depression? Probably not. Although I have never tried them to treat my depression, there seems to be mounting scientific evidence in support of Psilocybin as a treatment option for cases of treatment-resistant depression. These …