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Guanfacine Eases Hyperactivity in Autism; Inflammation Theory Untested

MHD card showing a teal prefrontal dendrite with a magnified membrane of closed HCN channels and an amber microglia cell inside a dashed outline, illustrating that guanfacine eased hyperactivity in autistic children while its anti-inflammatory role remains untested.

Guanfacine, a non-stimulant ADHD medication, reduced hyperactivity in autistic children in a placebo-controlled trial. A 2026 review argues it may also steady prefrontal brain signaling and calm the brain’s immune cells, but that immune effect has never been tested with guanfacine itself.1 Research Highlights Hyperactivity fell in the largest autism trial: in 62 autistic children, …

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Neurofeedback For ADHD: Is It An Effective Treatment?

Neurofeedback is a practice devised to optimize the electrical activity within a person’s brain a.k.a. adjust their brain waves.  It is based on the premise that abnormal electrical activity in certain regions of the brain may contribute to various psychological conditions and may compromise mental performance.  The goal of neurofeedback is to correct electrical abnormalities …

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What’s the Difference Between ADD and ADHD?

What’s the difference between ADD and ADHD? ADD stands for “attention deficit disorder” while ADHD stands for “attention-deficit hyperactivity disorder.” There really isn’t much of a difference other than in ADHD, there is “hyperactivity.” Both are characterized by extreme deficits and/or inability to focus and pay attention. Some would suggest that the term ADD has …

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