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AI Levodopa Timing Improved UPDRS 4.4 Points in 5 Parkinson Patients

MHD featured image for AI-guided levodopa dosing in Parkinson's disease.

A 2026 open-label feasibility trial involving 5 Parkinson’s disease patients found that app-randomized levodopa timing was associated with a mean 4.4-point improvement on the Unified Parkinson’s Disease Rating Scale, but the signal missed conventional statistical significance at p = 0.063.1 The narrow conclusion is feasibility: this was a dosing experiment that justified a blinded controlled …

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Survivors RESET Reduced Stress, Weight in Black Breast Cancer Survivors

MHD featured image for stress management and behavioral weight loss in Black breast cancer survivors.

A 2026 single-arm Survivors RESET study enrolled 20 Black female breast cancer survivors with obesity and elevated stress, then met its enrollment, retention, and adherence feasibility benchmarks while missing its stricter satisfaction benchmark by 5 percentage points.1 Weight fell by 2.4 kg and perceived stress fell by 6.9 PSS-10 points over 4 months, but without …

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