Cannabis users often say the drug helps them blunt stressful memories. A 2026 randomized trial of 36 healthy adults tested low-dose oral THC against placebo during retrieval of a standardized lab stressor, and on every subjective and physiological measure that mattered, THC did nothing.1 Research Highlights 36-adult, 3-arm RCT: participants got placebo, 5 mg oral …
Chronic stress is a candidate mechanism for both depression and addiction risk. A 2026 mouse study found that 28 days of unpredictable chronic mild stress increased striatal dopamine D1 receptor binding by 22–48% across nearly every region examined, plus more selective D2 receptor increases — pointing to a stress-driven shift in reward signaling that may …
Recent research has shed light on the potential benefits of cannabis-based medicinal products (CBMPs) in treating Generalized Anxiety Disorder (GAD), especially in patients with sleep disturbances. Recent research explored the effectiveness of CBMPs on GAD, the role of sleep quality in treatment outcomes, and the incidence of adverse events. Highlights: CBMPs Show Promise in Treating …