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AI Levodopa Timing Improved UPDRS 4.4 Points in 5 Parkinson Patients

MHD featured image for AI-guided levodopa dosing in Parkinson's disease.

A 2026 open-label feasibility trial involving 5 Parkinson’s disease patients found that app-randomized levodopa timing was associated with a mean 4.4-point improvement on the Unified Parkinson’s Disease Rating Scale, but the signal missed conventional statistical significance at p = 0.063.1 The narrow conclusion is feasibility: this was a dosing experiment that justified a blinded controlled …

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iSupport-Malaysia Dementia Caregiver Program Scored 74.3 on Usability

A 2026 mixed-methods preprint found that iSupport-Malaysia, a multimedia web-based dementia caregiver psychoeducation program, reached a good System Usability Scale score of 74.3. That is enough to justify pilot testing, but not enough to claim caregiver mental-health benefit: 33.3% of usability-test participants failed sign-up, 20.0% failed search, and Loh et al. did not measure burden, …

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