Mental Health DailyResearch. Evidence. Perspective.Published research on cerebrospinal fluid.
In a small Swedish trial substudy, psilocybin lowered galanin and noradrenaline in spinal fluid compared with niacin, and a bigger galanin drop was linked to bigger mood improvement (r = 0.5…
Read articleA 2022 Nature Communications study used non-contrast 3D T2-FLAIR magnetic resonance imaging (MRI) to map human brain lymphatic signals in living people, including apparent channels from cran…
Read articleA 2026 systematic review found that microglia-related immune signals do not line up cleanly with psychiatric diagnosis labels: major depression showed frontolimbic TSPO-PET increases, while …
Read articleA 2026 Nature Neuroscience study found that awake mouse brain motion was driven mainly by locomotion-linked abdominal muscle activity, not by respiration or cardiac rhythm; the researchers m…
Read articleA 2026 targeted metabolomics study of knee osteoarthritis found 33 altered serum metabolites and 10 altered cerebrospinal-fluid metabolites, but the symptom signal split by compartment: seru…
Read articleA 2026 cerebrospinal-fluid proteomics preprint involving 87 amyotrophic lateral sclerosis (ALS) patients, 89 healthy controls, and 61 neurological controls reported 399 ALS candidate protein…
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