A 2025 scoping review of 292 adult ADHD randomized controlled trials found that 49.7% allocated diagnosis without a general psychopathology assessment, and only 35% reported that psychiatrists or psychologists assigned the ADHD diagnosis. Research Highlights 292 adult ADHD RCTs were reviewed: Studart et al. screened 706 PubMed records and included 292 randomized controlled studies.1 49.7% …
A 2026 case-control study found that treatment-naive adults with attention-deficit/hyperactivity disorder (ADHD) had much lower serum SIRT-1, Nrf-2, and HO-1 than matched controls, while TNF-α did not differ. The pattern points more toward impaired antioxidant-defense regulation than a simple broad-inflammation story. Research Highlights Antioxidant-defense markers were lower: adults with ADHD had lower SIRT-1 (9.36 vs. …
A 2026 study of 958 adults entering Japanese multidisciplinary pain centers found that 17.1% screened positive for ADHD, rising to 27.4% among patients whose average pain was NRS 9-10; ASD screening was 4.4% overall and did not show the same pain-intensity signal.1 Research Highlights ADHD screening was elevated in tertiary pain care: 164 of 958 …