Mental Health DailyResearch. Evidence. Perspective.Published research on substantia nigra.
A 2026 mouse study found that Theiler’s murine encephalomyelitis virus (TMEV) injected into the substantia nigra produced persistent Parkinson’s-like motor signals through 20 weeks, includin…
Read articleA 2026 Nature Neuroscience study from the Igarashi lab proposes a circuit-level answer for why the lateral entorhinal cortex (LEC) is the first cortical region to falter in Alzheimer’s: dopa…
Read articleA 2026 iScience study recorded 27 substantia nigra neurons during deep-brain-stimulation surgery in 11 Parkinson’s disease patients and found that prior reward shaped both putative dopamine-…
Read articleA 2026 Parkinson’s disease study used gene-expression data and genome-scale metabolic modeling to predict patient-level metabolite patterns, then separated 104 patients into 3 metabolic subg…
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