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150 mg Caffeine Did Not Trigger Panic in Panic Disorder Trial

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A randomized crossover trial found that 150 mg caffeine did not increase subjective anxiety, interoceptive attention, or anxiety from body sensations in 29 people with panic disorder compared with 53 healthy controls.1 The result runs opposite the hypothesis, but it does not make caffeine inert: caffeine still increased physiological arousal, costly avoidance, and attention problems …

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Trauma Disrupts Parent-Child Fear Extinction in Youth With PTSD Symptoms

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A 97-dyad adolescent fMRI study found that trauma-exposed youth with high posttraumatic stress symptoms did not use parent-observed safety learning in the usual way: their arousal rose to a safety cue during vicarious extinction, F(1,159) = 4.81, p = 0.029, and parent-child physiological synchrony no longer predicted lower skin conductance during early safety learning.1 The …

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