Mental Health DailyResearch. Evidence. Perspective.Published research on rat model.
Cocaine relapse circuitry looks different when alcohol is part of the history. In a rat model, inhibiting prelimbic cortex neurons projecting to the nucleus accumbens core blocked cue-trigge…
Read articleA 40-rat early-life visceral stress study found auditory pathway sensitization without hearing-threshold loss: neonatal colorectal distension produced IBS-like visceral hypersensitivity, nor…
Read articleA 2026 Communications Biology rat study found that enriched housing reversed early-life-stress visceral hypersensitivity and depression-like behavior by normalizing a CB1 receptor-linked pre…
Read articleA 2026 Parkinsonism study involving 63 male rats found that Antrodia cinnamomea plus citrate-stabilized silver nanoparticles reduced 6-OHDA motor, oxidative-stress, inflammatory, α-synuclein…
Read articleSemaglutide is not close to being an approved cocaine-use-disorder medication, but a 2026 rat study gives the idea a more demanding preclinical test than ordinary self-administration experim…
Read articleA 2026 rat study estimated that adult hippocampal neurogenesis added 670,000 dentate gyrus granule neurons from 2 to 18 months of age, but the total dentate gyrus population grew by only 385…
Read articleA 2026 eLife study recorded 3,881 lateral orbitofrontal cortex units in rats and found that prior cocaine use made the OFC over-distinguish task positions that controls treated as functional…
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