olfactory dysfunction

Published research on olfactory dysfunction.

BrainOct 26, 2026

Alzheimer's Smell Loss Linked to Weaker Antioxidant Defenses in the Nose

In 144 Finnish adults, smell loss rose from healthy aging to MCI to Alzheimer's, and nasal smell-tissue cells from MCI and Alzheimer's donors showed lower NRF2 antioxidant gene activity in a…

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BrainJul 8, 2026

Alzheimer’s Smell Loss Linked to Early Locus Coeruleus Axon Damage

A 2025 Nature Communications study found that Alzheimer’s-like mice lost locus coeruleus noradrenergic axons in the olfactory bulb early: 14% loss by 2 months, 27% by 3 months, and 33% by 6 …

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BrainJun 15, 2026

Olfactory MRI Radiomics Link pTau217 to Alzheimer’s Cognition

A 2026 multi-cohort Alzheimer’s disease study found that MRI radiomics from the hippocampus and amygdala linked plasma pTau217 and smell identification to cognitive impairment — with more ad…

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