Nrf2

Published research on Nrf2.

BrainOct 26, 2026

Alzheimer's Smell Loss Linked to Weaker Antioxidant Defenses in the Nose

In 144 Finnish adults, smell loss rose from healthy aging to MCI to Alzheimer's, and nasal smell-tissue cells from MCI and Alzheimer's donors showed lower NRF2 antioxidant gene activity in a…

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Neurodegenerative DiseasesJun 6, 2026

C9orf72 ALS Poly-GR Drives Ferroptosis via Nrf2-Slc7a11

A 2026 Cell & Bioscience study found that poly-GR, one of the toxic dipeptide-repeat proteins produced in C9orf72-linked amyotrophic lateral sclerosis (ALS), pushed motor neuron-like cells t…

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