natural language processing Archives

PTSD Trauma Memories Are Encoded in Hippocampal Semantic Maps

by GLOOM

Photoreal illustration of the hippocampus with semantic encoding pathways highlighted, representing trauma memory processing in PTSD.

A 2026 fMRI study of 79 women with interpersonal-violence-related PTSD found that the hippocampus does encode the meaning of autobiographical trauma narratives, t(140) = 4.05, p < 0.001, even though average hippocampal encoding did not rise for trauma vs. neutral memories. Research Highlights Hippocampal semantic encoding was significant: Cisler et al. analyzed 3,928 narrative sentences …

Machine Learning Predicts Clozapine Initiation in Schizophrenia

by GLOOM

Photoreal illustration of an electronic health record dashboard with clinical text and a model output highlighted, representing ML prediction in psychiatry.

Clozapine is the only medication with proven efficacy for treatment-resistant schizophrenia, yet most eligible patients wait years before starting it. A 2026 paper by Perfalk and colleagues trains a machine-learning model on routine electronic health record data to flag candidates earlier.1 Research Highlights Clozapine is the only evidence-based treatment for treatment-resistant schizophrenia (TRS), but the …