Depressive Symptoms Rose 4 Years Before Death in Twins
In a 2,411-person multinational twin-consortium study, depressive symptoms increased significantly as death approached. The strongest design check compared twins directly: twins who died had larger terminal symptom increases than co-twins who survived at least 4 more years. Research Highlights Terminal mood change was visible: Petkus et al. found accelerated depressive-symptom increases roughly 4.3 years before …