Methadone was originally developed in Germany during the 1930s as a synthetic alternative to opium. Post World War II, the United States obtained all research records for the substance and noted that it was less sedating and less of a respiratory depressant than morphine. In 1947, Methadone was approved by the FDA for the treatment …
The technical definition of a drug is “any chemical substance that affects the central nervous system.” Determining the most addictive drugs has been a challenge for researchers and results have been controversial throughout the years. Additionally agreeing on a proper definition for “addiction” and criteria by which it can be measured is somewhat difficult. The …
ALKS-5461 is a new drug that is being developed by the company Alkermes as an alternative to SSRI’s for the treatment of depression. ALKS-5461 (its trial name) is a combination of both buprenorphine (suboxone) and samidorphan, and is regarded as a non-addictive opioid modulator and antidepressant. It is currently being developed specifically as an antidepressant …
Suboxone (Buprenorphine) is a medication that is primarily used to help individuals that are struggling with opiate addiction. This substance works as a semi-synthetic opioid agonist on the Mu receptor of the brain. In high doses it works to treat people that are trying to kick their addiction with opiates. In lower doses, it can …
Suboxone (Buprenorphine) is a medication that is used by people withdrawing from narcotics (opioids). It helps alleviate withdrawal symptoms and most people end up able to experience a smooth withdrawal while on this particular drug. In people that have either extreme or treatment-resistant depression, many have turned to trying a variety of drugs besides that …