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Parkinson’s Visual Hallucination Mouse Model Hit AUC 0.96

MHD featured image for Parkinson's visual hallucination mouse model behavior classification.

A 2026 Parkinson’s disease mouse study reported that benzhexol hydrochloride induced a measurable hallucination-like behavior state in 6-OHDA parkinsonian mice, and an integrated behavior classifier separated that state from non-PDVH mice with AUC = 0.96 and Youden index = 0.875.1 The careful interpretation is behavioral modeling, not proof that mice had human visual hallucinations. Research …

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Benadryl (Diphenhydramine) For Anxiety: A Makeshift, Last-Resort Option?

Benadryl is a widely-recognized brand name for popular over-the-counter (OTC) antihistaminergic products containing diphenhydramine (U.S. & Canada), a chemical of the ethanolamine classification.  Diphenhydramine was initially discovered in 1943 by professor and chemist George Rieveschl while attempting to synthesize alternatives to scopolamine.  Just several years after its synthesis, diphenhydramine received FDA approval in 1946 as a …

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