MentalHealthDaily

GLP-1 Drugs Reduced Sleep Apnea AHI by 13.89 Events per Hour

by GLOOM

MHD featured image for GLP-1 receptor agonists reducing sleep apnea severity and weight.

A 2026 meta-analysis of 4 randomized trials found that GLP-1 receptor agonists reduced obstructive sleep apnea severity by 13.89 apnea-hypopnea events per hour compared with placebo, alongside 12.46 kg more weight loss than placebo.1 The effect looks clinically meaningful for obesity-linked sleep apnea, but high heterogeneity means the result should not be flattened into “GLP-1 …

Smoking Linked to 1.75x Higher Sleep Apnea Severity in Pomerania Study

by GLOOM

MHD featured image for smoking history and obstructive sleep apnea severity in a population polysomnography study.

A 2026 population-based polysomnography study involving 1,206 adults found current smokers had 1.75x higher odds of worse obstructive sleep apnea severity than non-smokers or occasional smokers after adjustment for age and body mass index. Former smokers showed almost the same overall signal — 1.76x higher odds than never smokers — but that part of the …