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Digital Mindfulness for GAD: Machine Learning Predicted App Engagement

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A 2026 machine-learning analysis of 110 adults with generalized anxiety disorder predicted 2-week digital mindfulness engagement with R2 = 82.1% in a top-10 predictor model, and the model favored mindfulness prompts over self-monitoring prompts for engagement (d = 1.447, p < .001).1 The calibrated read is that engagement with brief app-based mindfulness may be matchable, …

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Early Mental Illness Severity Tracks Genetics and Brain Volume in PRONIA

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A 2026 PRONIA preprint involving 727 discovery-sample participants found that early mental illness severity cut across psychosis risk, recent psychosis, and recent depression: groups with higher symptom severity also had poorer functioning, higher schizophrenia and depression polygenic risk, and lower gray matter volume. Research Highlights Severity crossed diagnostic labels: Ye et al. stratified 727 participants …

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PTSD Social Function Therapy Improved Family Function in Older Veterans

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A 2026 pilot randomized trial involving 36 older U.S. veterans with PTSD symptoms found that a structured social-function group therapy produced stronger signals for romantic and family functioning than a support group, with condition-by-time effects of eta-squared = 0.072 and eta-squared = 0.112. The same trial did not show a specific advantage for friendships and …

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Aripiprazole Oculogyric Crisis in Tourette Tics: 2 Cases at 20-30 mg

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A 2026 Neurological Sciences brief communication added 2 Tourette syndrome cases of aripiprazole-related oculogyric crisis — sustained, involuntary upward eye deviation from extraocular-muscle dystonia — after titration to 20 mg and 30 mg daily, with remission after dose reduction.1 Research Highlights 2 new Tourette cases: Cavanna et al. reported oculogyric crisis in females aged 16 …

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Bhagavad Gita and Yoga Reduced Healthcare-Worker Anxiety in 68-Person Trial

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A 68-person randomized trial in Indian healthcare workers found a narrow but useful pattern: combined yoga plus Bhagavad Gita teaching beat usual care immediately on GAD-7 anxiety scores (p = 0.009), while Gita teaching alone beat usual care at 45 days (p = 0.047).1 Yoga alone improved within its own arm, but it did not …

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