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Trazodone and Weight Gain: Causes & Individual Factors

Trazodone (Desyrel) is a medication that is approved for the treatment of depression. It is classified as an atypical antidepressant that functions as a “SARI” (serotonin antagonist and reuptake inhibitor). In addition to inhibiting the reuptake of serotonin, it also blocks excess serotonin at various receptor sites. It is believed that the combined effect of …

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Effexor and Weight Gain: Causes & Individual Variation

Effexor (Venlafaxine) is a common antidepressant medication that is classified as an SNRI. It functions by preventing reuptake of the neurotransmitters serotonin and norepinephrine. It differs from standard SSRI medications in that it also targets norepinephrine, which often elicits a stimulatory effect on the user. Some believe that increasing norepinephrine in addition to serotonin makes …

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Zoloft and Weight Gain: Causes & Influential Factors

Zoloft (Sertraline) is an antidepressant medication that has been around since 1991. It functions as an SSRI (selective-serotonin reuptake inhibitor) to increase extracellular levels of the neurotransmitter serotonin. The drug is considered effective at treating a variety of conditions including major depression, social anxiety disorder, panic attacks and obsessive-compulsive disorder. Despite being around since the …

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Serotonin Map of the Brain To Optimize Antidepressant Development

While many people find antidepressants helpful for managing major depression, others are unable to find them therapeutic. It has long been thought that the neurotransmitter serotonin is responsible for contributing to cases of depression. Researchers and pharmaceutical companies alike have long believed that serotonin is the primary underlying factor associated with poor mood and other psychological …

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Brintellix (Vortioxetine) Withdrawal Symptoms + How Long They Last

Brintellix (Vortioxetine) is considered an atypical antidepressant that was co-developed by pharmaceutical companies Lundbeck and Takeda. Most consider Brintellix to be a new antidepressant as of 2014 due to the fact that it was approved by the FDA in September of 2013. In clinical trials, it proved to demonstrate substantial efficacy for the treatment of …

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