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Probiotics & Synbiotics for the Metabolic Side Effects of Psychiatric Medications: Are They Effective? (2024 Review)

Patients with severe mental illnesses (SMI), such as schizophrenia and chronic depression, often face the challenge of managing weight gain and metabolic complications, side effects commonly associated with antipsychotics and antidepressants. These medications are known to induce increased appetite and weight gain, leading to long-term metabolic syndromes. Recent studies have evaluated into the role of …

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Ketogenic Diet for ADHD Treatment via Gut Microbiome Modulation (2023 Study)

Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder commonly found in children, characterized by symptoms such as inattention, hyperactivity, and impulsivity. Recent research has revealed a connection between gut microbiota and neuropsychiatric disorders like ADHD. A new study suggests that the ketogenic diet could provide therapeutic benefit in ADHD by modulating gut bacteria and …

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Detecting Misdiagnosed Bipolar Disorder via MRI Brain Connectivity Analysis (2024 Study)

Bipolar Disorder (BD) and Major Depressive Disorder (MDD) are two of the most prevalent mood disorders, yet they are often misdiagnosed due to overlapping symptoms. This misdiagnosis can lead to inadequate treatment and worsened patient outcomes. However, recent advances in functional magnetic resonance imaging (fMRI) offer a promising solution to this challenge. By analyzing brain …

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KNT-127 for Anxiety: Delta Opioid Receptor Agonist via PL-BLA Pathway (2023 Study)

Recent scientific advancements have illuminated the crucial role of the prelimbic cortex to basolateral amygdala (PL-BLA) pathway in regulating anxiety-like behaviors. Utilizing cutting-edge optogenetic techniques and selective delta-opioid receptor (DOP) agonists, researchers have begun to decode the complex neural circuitry underlying anxiety disorders. Highlights: PL-BLA Pathway Significance: The connection between the prelimbic cortex (PL) and …

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Medical Cannabis for Generalized Anxiety Disorders & Sleep Disturbances (2023 Study)

Recent research has shed light on the potential benefits of cannabis-based medicinal products (CBMPs) in treating Generalized Anxiety Disorder (GAD), especially in patients with sleep disturbances. Recent research explored the effectiveness of CBMPs on GAD, the role of sleep quality in treatment outcomes, and the incidence of adverse events. Highlights: CBMPs Show Promise in Treating …

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Psychobiotic “Lactobacillus plantarum” (JYLP-326) for Test Anxiety in Students (2023 Study)

Test anxiety among college students is a significant concern, affecting their mental and physical well-being. A new study suggests that a probiotic/psychobiotic intervention (Lactobacillus plantarum) could significantly alleviate anxiety, depression, and insomnia, with changes observed in the gut microbiota and fecal metabolites. Highlights: Prevalence of Test Anxiety: 20%-40% of college students experience test anxiety, often …

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Vortioxetine Efficacy for Major Depression & Comorbid Anxiety (2023 Study)

The RELIEVE study provides pivotal insights into the effectiveness of vortioxetine in treating patients with Major Depressive Disorder (MDD) co-morbid with Generalized Anxiety Disorder (GAD). A subgroup analysis of the observational study highlights significant improvements in patient functioning, depression severity, cognitive symptoms, and quality of life. The findings underscore vortioxetine’s potential as a beneficial treatment …

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