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Statins and Dementia Risk: No Long-Term Signal in 322,358 Patients

Statins do not look like a dementia-prevention drug, but they do not look like a dementia hazard either. In 322,358 Kaiser Permanente Northern California patients followed for an average of 11.8 years, dementia diagnoses rose right after statins were started, then flattened: after the first year, the hazard ratio for Alzheimer’s disease and related dementias …

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Statins & Depression: Antidepressant Effect by Lowering Cholesterol?

Statins are among the most commonly prescribed medications worldwide. While best known for lowering cholesterol, emerging evidence suggests that statin drugs may also impact mental health – but in complex, and sometimes contradictory, ways. Key Facts: Animal and some human studies show statins may have antidepressant effects by altering neurotransmitters, promoting neurogenesis, and reducing inflammation. …

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