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NeuroMark SPECT Found 23 Schizophrenia Perfusion Network Changes

MHD featured image for NeuroMark SPECT schizophrenia perfusion-network research.

A 2026 medRxiv preprint built a reusable NeuroMark SPECT template from 2 large independent component analysis rounds, then applied it to 137 schizophrenia patients and 76 controls; after false-discovery-rate correction, 23 of 68 perfusion components differed between groups.1 Those data support infrastructure for comparing SPECT perfusion networks across datasets, with standalone schizophrenia diagnosis left outside …

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Brain Imaging Techniques (Neuroimaging)

Brain imaging (neuroimaging) was invented in the 1880s by Angelo Mosso, who devised a technique referenced as the “human circulation balance.”  This technique was able to assess how blood was redistributed throughout the brain as an individual experienced emotion and/or engaged in intellectual tasks.  It wasn’t until the early 1900s that a newer, improved brain …

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