magnetoencephalography Archives

Football Head Impacts Linked Cortical Slowing to NET and BDNF Maps

by GLOOM

MHD featured image for adolescent football head impacts and cortical slowing maps.

A 91-player adolescent football preprint mapped head-impact-related cortical slowing onto brain receptor and gene-expression maps: concussion-related slowing aligned with norepinephrine transporter density, r = 0.43, and alpha-4 beta-2 nicotinic receptor density, r = 0.50, while aligning inversely with dopamine D2, BDNF, and APOE maps.1 The result is a mechanistic clue about where head-impact physiology may …

REDDI MEG Classifier Separated 4 Neurodegenerative Diseases at 0.81

by GLOOM

MHD featured image for REDDI MEG differential diagnosis research.

A 2026 medRxiv preprint found that REDDI, a resting-state magnetoencephalography machine-learning pipeline, separated mild cognitive impairment, multiple sclerosis, Parkinson’s disease, and amyotrophic lateral sclerosis with 0.81 ± 0.04 balanced accuracy across 5 folds.1 That is a meaningful jump over the prior 67.1% MEG benchmark, but it is still research-stage decision support rather than a clinical …