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Autoimmune Focal Epilepsy: Antibody Testing and Immunotherapy

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A 2026 structured review of autoimmune drug-resistant focal epilepsy argues for a narrow but clinically important claim: immune mechanisms can make seizures refractory in selected patients, but the evidence supports targeted testing and immunotherapy triage rather than treating every medication-resistant seizure disorder as autoimmune. Research Highlights Autoimmune epilepsy is a subset: Kunecki et al. estimated …

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Dynamic FDG-PET Signal Quality Beats Static PET in Focal Epilepsy

MHD featured image for dynamic FDG-PET signal quality in focal epilepsy neuroimaging.

A 2026 medRxiv study of 30 adults with drug-resistant focal epilepsy found that dynamic FDG-PET had higher model-adjusted signal quality than static PET in most brain regions, including >80% posterior probability of superiority in 29 of 36 regions. Research Highlights Dynamic PET beat static PET: interictal dynamic FDG-PET showed higher signal quality than static PET …

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