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Resting Brain Connectivity Predicts Fear Extinction Learning

Photoreal illustration of brain network connections in the fear-extinction circuitry, with imagery linking amygdala and prefrontal regions.

A 2026 multimodal MRI analysis of 509 healthy adults found that fear acquisition, extinction learning, and renewal were not predicted by one generic “fear circuit” score: functional connectivity predicted acquisition, structural connectivity predicted extinction, and effective connectivity was the only renewal signal.1 The extinction result is the clinically interesting piece because exposure therapy depends on …

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Bergen 4-Day Treatment (B4DT) Appears Effective for OCD in Adolescents (2024 Study)

Obsessive-Compulsive Disorder (OCD) in adolescents is a challenging condition, marked by intrusive thoughts and compulsive behaviors that significantly impair daily functioning. Recent studies have spotlighted the Bergen 4-Day Treatment (B4DT), an intensive, concentrated therapy approach showing promising outcomes in treating adolescents with OCD across various sites in Norway. This innovative method, comprising prolonged sessions of …

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