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Long-Term Antidepressant (SSRI) Use Increasing: Overprescription & Withdrawal Hesitancy

The rise in antidepressant prescribing, especially selective serotonin reuptake inhibitors (SSRIs) since the 1980s, is a complex phenomenon with broad implications for public health. While these medications are crucial for many, the increase in long-term use has raised concerns about overprescription, side effects, and withdrawal challenges. Key Facts: Rising Prescriptions: Antidepressant prescriptions, particularly SSRIs, have …

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Fetzima (Levomilnacipran) Withdrawal Symptoms

Fetzima (Levomilnacipran), is a serotonin-norepinephrine reuptake inhibitor (SNRI) that was approved by the United States FDA in 2013 for the treatment of major depressive disorder.  It was engineered to be a spinoff (or some might suggest an upgraded or slightly modified version) of the drug Savella (Milnacipran). Comparatively, Fetzima solely contains the levorotatory enantiomer of …

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Rexulti (Brexpiprazole) Withdrawal Symptoms: What You Should Know

Rexulti (Brexpiprazole) is an atypical antipsychotic that is most commonly utilized as a pharmacologic intervention for the management of schizophrenia, and in some cases, as an add-on (adjunct) treatment for refractory major depressive disorder.  Throughout the central nervous system, the medication exerts neurophysiologic effects across dopaminergic, serotonergic, noradrenergic, and histaminergic targets. Receptor sites most targeted …

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Tianeptine Withdrawal Symptoms

Tianeptine, also referred to under the brand names “Stablon” and “Coaxil,” is an antidepressant originally discovered and patented in the 1960s by the French Society of Medical Research.  The drug is primarily utilized for the treatment of major depressive disorder in France and European countries.  In some cases, tianeptine is also utilized for the management …

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Cymbalta Lawsuits: Users Suing Eli Lilly Over Undisclosed Withdrawal Symptoms

It appears as though the pharmaceutical juggernaut Eli Lilly is facing major legal backlash for failure to disclose discontinuation effects associated with their medication Cymbalta (Duloxetine).  Cymbalta is an SNRI antidepressant that was approved in August 2004 for the treatment of major depression.  A woman named Claudia Herrera has been making news headlines because she …

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