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Pantoprazole (Protonix) vs. Omeprazole (Prilosec)

Pantoprazole and Omeprazole are medications classified as proton-pump inhibitors (PPIs) and are commonly prescribed for the management of medical conditions in which stomach acid reduction is of therapeutic benefit. Chemists at Byk Gulden, a subsidiary of Altana (a German chemical company), are credited with the synthesis of pantoprazole in 1985 – whereas Swedish chemists at …

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Lexapro (Escitalopram) vs. Prozac (Fluoxetine)

Lexapro (escitalopram) and Prozac (fluoxetine) are two medications within the selective-serotonin reuptake inhibitors (SSRI) classification that are commonly administered for the treatment of neuropsychiatric disorders.  The development of Lexapro (escitalopram) was initiated in 1997 by Lundbeck and Forest Laboratories – whereas the development of Prozac (fluoxetine) was initiated in the 1970s by chemists (Bryan Molloy …

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Pregabalin (Lyrica) vs. Gabapentin (Neurontin)

Lyrica (pregabalin) and Neurontin (gabapentin) are both classified as “gabapentinoids” (i.e. α2δ ligands).  As gabapentinoids, Lyrica (pregabalin) and Neurontin (gabapentin) are chemical analogues of the inhibitory neurotransmitter GABA (gamma-aminobutyric acid) that interact with α2δ subunit-containing voltage-dependent calcium channels. Development of gabapentin (Neurontin) was initiated in the 1970s by chemists at the pharmaceutical company Parke-Davis – …

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Celexa (Citalopram) vs. Lexapro (Escitalopram): Which Is Better?

Celexa (citalopram) and Lexapro (escitalopram) are chemically-analogous medications within the selective-serotonin reuptake inhibitor (SSRI) classification that are regularly prescribed for the management of neuropsychiatric disorders.  Chemically, Celexa contains enantiomers S-citalopram and R-citalopram – whereas Lexapro solely contains S-citalopram (hence its chemical name “es-citalopram”). The chemical “citalopram” (Celexa) was originally synthesized in 1972 by scientists at …

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Lexapro (Escitalopram) vs Zoloft (Sertraline): Extensive Comparison

Lexapro (escitalopram) and Zoloft (sertraline) are medications of the selective-serotonin reuptake inhibitor (SSRI) classification utilized most commonly for the management of major depressive disorder (MDD).  Lexapro was co-developed by the pharmaceutical companies Lundbeck and Forest Laboratories (starting in 1997) and received U.S. FDA approval for medical use in 2002. Zoloft was developed by the pharmaceutical …

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Vistaril (Hydroxyzine) vs. Xanax (Alprazolam)

Hydroxyzine, also referred to under its brand names “Vistaril” (hydroxyzine pamoate) and “Atarax” (hydroxyzine hydrochloride), is a first-generation diphenylmethylpiperazine antihistamine.  Alprazolam, most commonly referred to under its brand name “Xanax,” is a benzodiazepine, or more specifically, a triazolobenzodiazepine anxiolytic. In the United States, Vistaril is medically approved as an adjunctive treatment for: psychoneurosis-related anxiety and …

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Temazepam vs. Xanax: Comparison

Restoril (Temazepam) and Xanax (Alprazolam) are medications of the benzodiazepine classification that originally received U.S. FDA approval in 1981 as treatments for distinct medical interventions.  Temazepam was approved as a short-term treatment for insomnia (intended to be used for 7 to 10 days) – whereas Alprazolam was approved as a treatment for generalized anxiety disorder …

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