hit counter

Low-Level Lead Linked to Infant Neurodevelopment Through DNA Methylation

MHD featured image for low-level lead exposure, infant neurodevelopment, and FAM50B/PTCHD3 DNA methylation.

A 2026 prospective birth-cohort study in southern China linked mean cord-blood lead of 15.30 μg/L to lower infant neurodevelopmental scores across all 5 Ages and Stages Questionnaire domains, even though only 1.13% of samples exceeded 50 μg/L.1 A second finding was mechanistic: part of the lead-development association statistically ran through FAM50B/PTCHD3 DNA methylation, an epigenetic …

Read more

EEG Alpha Density Decreased in Children, Increased in Adults

Photoreal illustration of children and adults with overlay of EEG brain rhythms, conveying developmental differences in sleep effects on brain activity.

A 2026 eNeuro analysis of 163 people ages 3.5–24.7 found that wake EEG amplitude behaved like a sleep-pressure marker, but wake alpha-density changed in opposite directions across development: it decreased overnight in children and increased overnight in adolescents and adults.1 Research Highlights Alpha density flipped by age: In 163 participants ages 3.5–24.7, oscillation density showed …

Read more