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Provigil (Modafinil) For Depression: An Effective Off-Label Treatment

Provigil (Modafinil) is a eugeroic drug that was originally approved in 1998 for the treatment of excessive daytime sleepiness associated with narcolepsy, shift work sleep disorder, and obstructive sleep apnea.  Despite never attaining FDA approval for the treatment of depression, many anecdotal reports highlight the efficacy of Provigil as an antidepressant.  The drug tends to …

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Dexedrine vs. Adderall: Comparison

Dexedrine is a psychostimulant drug primarily used to treat severe cases of ADHD and narcolepsy.  The active ingredient in Dexedrine is “dextroamphetamine” which is regarded as the “right-handed” stereoisomer of the molecule amphetamine.  Dextroamphetamine is considered a popular military stimulant, and has been utilized throughout history such as in World War II to offset fatigue …

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Concerta vs. Vyvanse: Comparison

Methylphenidate is considered the first medication approved for the treatment of the condition known as “hyperactivity” in the 1960s.  As attention-deficit/hyperactivity disorder gained more mainstream attention in the 1990s, the number of diagnoses continued to skyrocket, increasing the demand for new treatments.  By the year 1996, mixed amphetamine salts (i.e. Adderall) were approved for the …

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Nuvigil (Armodafinil) vs. Provigil (Modafinil): Comparison

Nuvigil and Provigil are both drugs that were approved by the FDA for the treatment of excessive daytime sleepiness.  Both drugs act as eugeroics and are considered “wakefulness-promoting agents” in that they are distinct from more potent, habit-forming psychostimulants (e.g. Adderall).  Provigil was initially approved in the late 1990s to help treat narcolepsy. Although the drug …

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Focalin vs. Adderall: Comparison

The pharmaceutical market is saturated with drugs intended to treat ADHD.  The number of different options is often helpful for patients that may not respond to the first drug that they try.  Although there are a variety of different options, the two most popular formulations are those containing mixed amphetamine salts and those containing methylphenidate. …

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Strattera vs. Adderall: Comparison

An overwhelming majority of medications used to treat ADHD (attention-deficit/hyperactivity disorder) are classified as psychostimulants.  Although psychostimulant drugs tend to have an immediate effect in reducing symptoms of attentional deficits and hyperactive behavior, they have a high potential for abuse.  Furthermore, there is something to be said for the potential that long-term psychostimulant use may …

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