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Transcranial Photobiomodulation For Depression: Near-Infrared Light & Laser Therapy

Photobiomodulation involves the targeted administration of light frequencies to modulate biological function for the treatment of medical conditions and/or to expedite healing in the aftermath of a physical injury.  It was Niels Ryberg Finsen who was among the first to showcase the potential of photobiomodulation when he proved that sunlight rays were capable of killing …

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Buspar (Buspirone) For Depression: Exploring The Antidepressant Potential

Buspar (Buspirone) is a drug of the azapirone chemical classification that was engineered and patented in the 1970s by Mead Johnson.  It was later acquired by the pharmaceutical company Bristol-Myers Squibb and approved by the FDA in 1986 for the treatment of generalized anxiety disorder (GAD).  What’s unique about buspirone compared to other anxiolytics such …

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Whole-Body Hyperthermia For Depression: Turning Up The Heat To Enhance Mood?

Hyperthermia is defined as supraphysiological body temperature resulting from absorption and/or production of more heat than is dispelled.  Medically, local hyperthermia is often used as an adjunct to radiation and/or chemotherapy for the treatment of cancers.  It is thought that deliberate induction of hyperthermia to a cancerous region of the body increases the sensitivity of …

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Pindolol For Depression: A Useful Antidepressant Adjunct?

Pindolol is a beta blocker initially synthesized by the pharmaceutical company Sandoz in the 1960s.  As of 1977 it received FDA approval for the management of hypertension and was sold under the brand name “Visken.”  Pharmacologically, pindolol acts as a non-selective beta blocker, meaning it competitively binds to all 3 beta-adrenergic receptor sites (Beta-1, Beta-2, …

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Phentermine For Depression: Does It Improve Mood?

Phentermine is a sympathomimetic amine [derived from amphetamine] initially approved by the FDA in 1959 for the treatment of obesity.  Its usage in the treatment of obesity was considered ideal due to the fact that phentermine suppressed appetite through central modulation of norepinephrine, and peripherally mobilized fat stores through catecholaminergic upregulation. That said, in the …

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Minocycline For Depression: Antibiotics As Antidepressants?

Minocycline is a broad-spectrum antibiotic of the tetracycline classification, indicating that its chemical structure consists of 4 hydrocarbon rings.  The fact that minocycline has a broad-spectrum mechanism indicates that it targets a wide-range of pathogenic (Gram-positive and Gram-negative) bacteria.  In fact, when compared to other tetracycline drugs, minocycline is regarded as having the “broadest spectrum” …

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10 Best Probiotics For Depression & Anxiety: Gut-Brain Axis Modification

Microbiota is classified as an ecological community of microorganisms that share a specific host.  Within the human body it is estimated that there are trillions of microorganisms, accounting for approximately 1% to 3% of total body mass; equating to an average net weight of around 3 lbs.  Though scientists these days are attempting to elucidate …

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