MentalHealthDaily

Parkinson’s Metabolite Biomarkers Split 3 Patient Groups

by GLOOM

MHD featured image for Parkinson's disease metabolite biomarkers and patient metabolic subgroups.

A 2026 Parkinson’s disease study used gene-expression data and genome-scale metabolic modeling to predict patient-level metabolite patterns, then separated 104 patients into 3 metabolic subgroups that were partly reproduced in an independent 81-patient validation dataset. Research Highlights Patient-level modeling found heterogeneity: Abdik et al. predicted secretion tendencies for 802 analyzable metabolites across 104 postmortem substantia …

Genetic Risk for Low Vitamin D Linked to Lower Social Motivation in First-Episode Psychosis (2024 Study)

by GLOOM

Recent research reveals a notable association between vitamin D levels and the severity of negative symptoms in individuals with first-episode psychosis (FEP). A new study explored the genetic predisposition towards lower vitamin D levels and its impact on symptom severity in schizophrenia and related disorders. Highlights: Vitamin D & Psychosis Connection: Lower levels of vitamin …

Vitamin D for Prevention & Treatment of Parkinson’s Disease? (2023 Research)

by GLOOM

Parkinson’s disease (PD), a prevalent neurodegenerative brain disease, is marked by the loss of dopaminergic neurons in the substantia nigra. Recent research has illuminated the significant role of Vitamin D (VD) in the brain, particularly its neuroprotective effects on these neurons. Highlights: Vitamin D’s Role in the Brain: Beyond its well-known functions in bone health, …

Link Between Vitamin D Deficiency and Depression: Does Supplementation Help Symptoms?

by GLOOM

Vitamin D is a crucial component to maintaining both physical and mental health. It is utilized by our bodies to help keep our bones and teeth in good condition by maintaining correct phosphorous to calcium ratio. In fact, research has shown that low levels of vitamin D are associated with cardiovascular disease, cancer, osteoporosis, obesity, …