MentalHealthDaily

TMEV Viral Parkinson’s Mouse Model Caused 20-Week Dopamine-Lesion Behaviors

by GLOOM

MHD featured image for a viral Parkinson's mouse model using Theiler's murine encephalomyelitis virus.

A 2026 mouse study found that Theiler’s murine encephalomyelitis virus (TMEV) injected into the substantia nigra produced persistent Parkinson’s-like motor signals through 20 weeks, including apomorphine-induced rotations at every measured post-injection timepoint.1 The finding makes TMEV a useful viral-neuroinflammation model of dopamine-neuron injury, but it does not show that Theiler’s virus causes human Parkinson’s disease. …

Antrodia Silver Nanoparticles Reduced Parkinsonism Markers in 63 Rats

by GLOOM

MHD featured image for Antrodia silver nanoparticles and Parkinsonism oxidative-stress markers.

A 2026 Parkinsonism study involving 63 male rats found that Antrodia cinnamomea plus citrate-stabilized silver nanoparticles reduced 6-OHDA motor, oxidative-stress, inflammatory, α-synuclein, and apoptosis markers, while dopamine and acetylcholine recovery remained nonsignificant. The useful claim is a multitarget preclinical signal, not a Parkinson’s disease treatment recommendation. Research Highlights Combination treatment looked strongest: Tekiner et al. …