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SloCAD Sleep EEG-fMRI Maps Brain Network Deviations Before Diagnosis

MHD featured image for SloCAD sleep EEG-fMRI network deviation mapping.

A 2026 iScience paper used simultaneous sleep EEG-fMRI from 2 healthy cohorts totaling 24 people to build slow-wave-related BOLD reference maps and propose SloCAD, a framework for measuring how an individual’s slow-wave brain activity deviates from a healthy reference pattern.1 Research Highlights The proof of concept used 24 healthy participants: 2 independent cohorts (N1 = …

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Sleep Memory Cues Do Not Boost Parkinson’s Motor Learning

Photoreal illustration of an older adult sleeping with overlay of memory and brain oscillation imagery, conveying sleep-based learning intervention.

Auditory targeted memory reactivation during a 2-hour nap did not improve motor retention in 20 Parkinson’s disease patients or 20 healthy older adults, even though the same cues changed sleep physiology by reducing spindle density and increasing slow-wave density.1 Research Highlights First Parkinson’s TMR test: Micca et al. studied 20 Parkinson’s disease patients and 20 …

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