Ketamine Addiction After One Therapeutic Dose: How Rare Is It?
Research Highlights One published case is not a base rate. Roelandt and colleagues (2026) describe a 25-year-old multimorbid patient who developed severe ketamine addiction after a single 75 mg intranasal sub-anesthetic dose given for acute suicidality. It is N = 1, but it is now the second published case after Bonnet 2015 of post-clinical-use ketamine …