hit counter

Stress Suppressed Food-Cue Reward Through NTS A2 Dopamine Circuits

MHD featured image for stress, food cues, NTS A2 neurons, and dopamine reward circuitry.

A 2026 rat study found that foot-shock stress transiently reduced food-cue approach during the first 2 conditioned-stimulus trials (t = 2.807; P < 0.05), and inhibiting the nucleus of the solitary tract weakened that stress effect.1 The useful finding is selective: stress used an NTS-linked route to dampen cue-evoked VTA dopamine, while outcome-specific satiety reduced ...

Read more

tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)

In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option. This non-invasive brain stimulation technique targets specific brain regions to modulate activity and potentially alleviate symptoms. A recent study has shed light on the efficacy and safety of targeting …

Read more