psychiatric comorbidity Archives

Anxiety and Depression in COPD: 18% Diagnosed, Most Treated With Benzodiazepines

by GLOOM

MHD card showing glowing outlined lungs with a branching cyan bronchial tree and flowing breath-wave lines, illustrating a Lithuanian study in which 18% of people with COPD had a recorded anxiety or depression diagnosis.

Nearly 1 in 5 people with COPD in Lithuania had a recorded diagnosis of anxiety or depression, according to a nationwide study of 64,246 patients. Anxiety was far more common than depression, and most patients who received medication were prescribed benzodiazepines.1 Research Highlights 18.1% had a recorded diagnosis: 11,608 of 64,246 adults with COPD in …

MDD and Alcohol Use Disorder Polygenic Scores Add 4.88% Prediction

by GLOOM

MHD featured image for MDD and alcohol use disorder polygenic risk.

A 2026 Add Health analysis found that combining major-depression and alcohol-use-disorder polygenic scores added 4.88% variance for comorbid MDD-AUD prediction, while same-trait scores added only 0.65% for MDD and 1.52% for AUD alone.1 The genetic signal is strongest where the clinical problem is hardest: depression plus alcohol-use disorder, not either diagnosis in isolation. Research Highlights …