MentalHealthDaily

Lurasidone Improves Positive Symptoms of Schizophrenia More Than Negative

by GLOOM

MHD featured image for Lurasidone PANSS Domains: Positive Symptoms Lead, Negative Lag.

Lurasidone is approved for schizophrenia and bipolar depression on the strength of acute trials that mostly reported a single number: the change in PANSS total score. A 2026 post-hoc analysis of the JEWEL Phase 3 trial pulls that number apart, looking separately at five symptom domains and at all 30 individual items of the PANSS …

Positive Symptoms of Schizophrenia: Hallucinations & Delusions

by GLOOM

Schizophrenia is a devastating mental illness that affects approximately 1% of the adult population in the United States. There are many symptoms of the illness, but a split dichotomy of what are called “positive” symptoms and “negative” symptoms. Positive symptoms are like adding something to the person’s experience such as hallucinations, delusions, paranoia, etc. In …