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Quetiapine Linked to Better Working Memory Scores in Schizophrenia

MHD card with an amber myelinated nerve fiber, quetiapine tablets, and a digits-backward memory sequence: quetiapine users with schizophrenia scored higher on hard working-memory tests, but myelin genes did not explain it.

A 2026 German-Austrian cohort analysis found that people with schizophrenia who were taking quetiapine scored modestly higher on demanding working-memory tests than sex- and age-matched patients who were not, with the largest gap at doses of 300 mg a day or less.1 Because patients were not randomized to quetiapine, this is an association; the advantage …

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