Prenatal PM2.5 Linked to Autism-Relevant Newborn Amino Acid Metabolism
A matched case-control study of 50 children with autism spectrum disorder and 50 controls found that newborn amino acid metabolism overlapped with both later autism diagnosis and prenatal air-pollution exposure.1 The central pathway, aspartate and asparagine metabolism, was associated with autism (p = 0.01), pregnancy PM2.5 (p < 0.001), first-trimester PM2.5 (p < 0.001), and …