Long COVID Fatigue Was Severe Without Clear Inflammation Biomarkers
A 2026 controlled study of 96 people found severe long-COVID fatigue across 3 validated fatigue scales, but the tested peripheral inflammation, cellular-stress, neuroprotection, and autoimmunity markers did not significantly differ by group or explain fatigue severity.1 The finding argues against a simple blood-marker story, not against the reality of long-COVID fatigue. Research Highlights Fatigue was …