MentalHealthDaily

Cholestatic Liver Injury Alters Thalamus Fatigue Genes

by GLOOM

MHD featured image for cholestatic liver disease, thalamus changes, fatigue, and TNF signaling.

A 2026 mouse study linked cholestatic liver injury to smaller thalamic volume than control injury-free mice, broad thalamus gene-expression changes, and partial pathway rescue after systemic tumor necrosis factor neutralization. Research Highlights Thalamic volume decreased: bile duct ligation (BDL; a mouse model of obstructive cholestatic liver injury) reduced thalamic volume vs. sham surgery by magnetic …

At What Age Is The Brain Fully Developed?

by GLOOM

It is widely debated as to which age the brain is considered “fully mature” or developed. In the past, many experts believed that the brain may have been done developing in the mid to late teens. Then along came some evidence to suggest that development may last until at least age 20. These days, a …