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Nighttime Caffeine Increased Impulsivity Through Dopamine in Fly Study

MHD featured image for nighttime caffeine, dopamine, and impulsive motor behavior.

A 2025 iScience study found that nighttime caffeine increased motor impulsivity in Drosophila, with dose-dependent loss-of-inhibition events across n = 30-32 flies per behavioral condition and stronger effects in female flies than male flies.1 The result does not prove that an evening coffee makes humans reckless, but it sharpens a neglected point: caffeine’s alertness benefit …

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BDNF Gene Transfection & Pramiprexole Combo Effectively Treat Parkinson’s Disease in Rat Models (2024 Study)

Parkinson’s disease (PD), a degenerative disorder that predominantly affects the motor system, has long been a challenging condition to manage due to its complex pathology and the limited efficacy of available treatments. However, recent research presents a beacon of hope through a novel combined therapy targeting the core of Parkinson’s disease’s neuronal degradation. This innovative …

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