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Blood microRNAs Linked to Hippocampal Atrophy in Rhineland Study

MHD featured image for blood microRNA signatures and hippocampal atrophy.

A 2026 Molecular Psychiatry analysis from the Rhineland Study found that blood-derived microRNA signatures were associated with hippocampal brain structure: 6 microRNAs linked cross-sectionally to left hippocampal volume, and 5 different microRNAs linked longitudinally to hippocampal atrophy rates.1 The result is biomarker-discovery evidence for brain aging, not a ready dementia blood test. Research Highlights Baseline …

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MicroRNA Biomarkers May Help Diagnose Schizophrenia

Schizophrenia (SZ) is a complex psychiatric disorder characterized by a myriad of symptoms, typically divided into positive, negative, and cognitive categories. Despite the prevalence and severity of this condition, current diagnostic methods are largely based on subjective clinical interviews and observations, leading to potential misdiagnosis and delayed treatment. Recent studies have focused on microRNAs (miRNAs) …

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