microglial activation Archives

Maternal COVID-19 and Autism Screening: 10.1% Positive MCHAT-R/F

by GLOOM

MHD featured image for maternal COVID-19 exposure, autism screening, and immune signatures.

A 745-child cohort found positive MCHAT-R/F autism screens in 22 of 218 children exposed to maternal SARS-CoV-2 infection during pregnancy (10.1%) vs. 30 of 527 pre-pandemic controls (5.7%; p = 0.03).1 The same 2026 analysis added a small serum-proteomics layer: exposed newborns who later screened positive showed altered immune and metabolic markers, but the paper …

Minocycline For Depression: Antibiotics As Antidepressants?

by GLOOM

Minocycline is a broad-spectrum antibiotic of the tetracycline classification, indicating that its chemical structure consists of 4 hydrocarbon rings. The fact that minocycline has a broad-spectrum mechanism indicates that it targets a wide-range of pathogenic (Gram-positive and Gram-negative) bacteria. In fact, when compared to other tetracycline drugs, minocycline is regarded as having the “broadest spectrum” …