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VNS After Failed Epilepsy Surgery Reduced Seizures 76% at 36 Months

Photoreal illustration showing an implanted vagus nerve stimulator and brain pathways, representing neuromodulation for drug-resistant epilepsy.

A 2026 CORE-VNS registry analysis found that implanted vagus nerve stimulation still produced large 36-month seizure reductions after failed intracranial epilepsy surgery: median all-seizure reduction was 76.3% with prior surgery vs. 76.6% without prior surgery.1 Research Highlights Prior surgery did not blunt the main VNS signal: CORE-VNS reported 76.3% median all-seizure reduction at 36 months …

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