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Neonatal Brain MRI Shows Gyri Are Connectivity Hubs by 38-44 Weeks

MHD featured image for neonatal MRI, cortical gyri, sulci, and early brain connectivity.

A 2026 developing Human Connectome Project analysis of 438 full-term neonates found that the newborn cortex already had an adult-like folding hierarchy: gyri connected most strongly to other gyri, sulci connected most weakly to other sulci, and structure-function coupling shifted near 41 to 42 weeks postmenstrual age.1 Research Highlights Gyri were already high-connectivity hubs: across …

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