Amitriptyline Water Pollution Impaired Male Guppy Spatial Accuracy
A 2026 Environmental Science & Technology experiment found that wild guppies still reduced maze solve times with practice after 11-day exposure to environmentally motivated amitriptyline concentrations, but exposed males made 26.35% to 34.21% more navigation errors than control males.1 The result is a sex-specific accuracy signal, not a blanket claim that antidepressant pollution erased learning. …