MentalHealthDaily

Striatal Dopamine Drops From Psychosis to Schizophrenia Remission

by GLOOM

Photoreal illustration of a brain with the striatum highlighted and dopamine synthesis pathways visualized, representing longitudinal PET imaging in schizophrenia.

The dopamine hypothesis of schizophrenia is the field’s longest-running mechanistic story, and most of its supporting evidence has been cross-sectional. A 2026 longitudinal PET study by Schulz and colleagues followed the same 28 patients across psychosis and early remission.1 Research Highlights The dopamine hypothesis of schizophrenia is the field’s longest-running mechanistic story. Cross-sectional 18F-DOPA PET …

What Causes Schizophrenia? Genetics, Environment, Brain Chemistry, Brain Structure

by GLOOM

Schizophrenia is a severe disease in which individuals are plagued with hallucinations, delusions, disorganized speech, as well as social dysfunction. Although an exact cause of the disease has not yet been discovered, researchers are aware that a number of factors may contribute to its development. Genetics, environment, brain structure, and brain chemistry can each be …